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Healthy lifestyle choices — including diet, exercise and weight control — provide the foundation for managing type 2 diabetes. However, you may need medications to achieve target blood sugar (glucose) levels. Sometimes a single medication is effective. In other cases, a combination of medications works better.

The list of medications for type 2 diabetes is long and potentially confusing. Learning about these drugs — how they’re taken, what they do and what side effects they may cause — will help you discuss treatment options with your doctor.

Diabetes treatment: Lowering blood sugar

Several classes of type 2 diabetes medicines exist. Each class of medicine works in different ways to lower blood sugar. A drug may work by:

  • Stimulating the pancreas to produce and release more insulin
  • Inhibiting the production and release of glucose from the liver
  • Blocking the action of stomach enzymes that break down carbohydrates
  • Improving the sensitivity of cells to insulin
  • Inhibiting the reabsorption of glucose in the kidneys
  • Slowing how quickly food moves through the stomach

Each class of medicine has one or more drugs. Some of these drugs are taken orally, while others must be injected.